Accurate Pain Reporting – APR

Accurate Pain Reporting – APR

Accurate Trial Data from Proven Training

Inaccurate Pain Reporting

Clinical trials of analgesics are plagued by the insensitivity of pain outcome measures due to the large variability in subjects’ ability to accurately report their pain, and their ability to discriminate effective drugs from placebo.

Industry Leading Accurate Pain Reporting Training

Accurate pain reporting is crucial to study success, but 20% to 30% of subjects enrolled in a pain trial are unable to report their pain accurately.  This impact is extremely detrimental, when there is less accuracy in pain reporting, there is more variability in pain scores among subjects. The greater the variability in pain scores, the more likely a trial is to fail.

With over 30,000 subjects and study staff already trained, we are the industry leaders in delivering evidence based, validated training solutions.

Proven to Work

A randomized controlled pilot study in patients with painful diabetic neuropathy (PDN) showed that subjects who undergo accurate pain reporting training can report their pain intensity more accurately and can better discriminate between active drug and placebo compared to subjects that do not undergo any training1

Our Accurate Pain Reporting Training has been evaluated for clarity, content, and relevance through a cognitive debrief study with OA patients2

  • 100% of patients note that the materials were helpful
  • Results showed that the materials are clear, relevant, and appropriate


  1. Treister R et al., Training Subjects to report their pain more accurately improves study power: Results of a randomized placebo-controlled study of pregabalin vs placebo in PDN. IASP, Japan, 2016
  2. Treister R et al., Development and Evaluation of Psychoeducational Accurate Pain Reporting Training Program. IASP Conference, Japan, 2016
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